Invasive negative breast cancer triangular

See other articles in PMC that cite the published article. MENA INV has been shown to drive resistance to targeted tyrosine kinase inhibitors in growth-factor elicited motility responses 28however its role in regulating responses to chemotherapeutic drugs has never been studied. Data pooled from 4 experiments, two technical replicates per experiment.

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Invasive negative breast cancer triangular
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MENA confers resistance to paclitaxel in triple-negative breast cancer

Our findings reveal a novel mechanism by which highly metastatic breast cancer cells can become resistant to taxanes. Tatsiana Kosciuk 1 David H. Our data reveal an interesting relationship between the response of highly metastatic cells to taxanes, as well as the effect of taxanes on highly metastatic cell populations in tumors, that could have important clinical implications.

Invasive negative breast cancer triangular
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Support Center Support Center. By western blot analysis detected using an anti-Mena monoclonal that recognizes an epitope shared in all known Mena protein isoforms 33 indicated that expression of all molecular species detected were significantly reduced in the T47D-ShMena cell invasive negative breast cancer triangular expression analysis of specific MENA isoforms was not performed. All measurements were repeated in triplicate. The publisher's final edited version of this article is available free at Mol Cancer Ther.

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