Some small studies have shown that tamoxifen may help lower the risk in women specifically with a BRCA2 gene mutation. An ambiguous result, also known as a variant of uncertain significance, occurs when the analysis finds a genetic variant that may or may not be associated with an increased risk of cancer.
If you want to learn more about family-related risk and genetics, you can visit the Lower Your Risk section of this site. A negative test result means that no BRCA gene mutation was found. Inherited BRCA gene mutations are responsible for about 5 to 10 percent of breast cancers and about 15 percent of ovarian cancers.
However, you may learn you have a gene variant that doctors aren't sure about. As soon as you consider having any genetic test, meet with a genetic counselor to determine whether it's appropriate for you and to discuss the potential risks, limitations and benefits of undergoing genetic testing. Medication to reduce your risk of cancer chemoprevention.
What you choose to do depends on many factors — including your age, medical history, prior treatments, past surgeries and personal preferences. If you don't have a mutation, this is considered a negative result.